Acrab efflux pump impacts on the survival of adherent-invasive escherichia coli strain lf82 inside macrophages

HIGHLIGHTS

• who: Giulia Fanelli from the Department have published the research work: AcrAB efflux pump impacts on the survival of adherent-invasive Escherichia coli strain LF82 inside macrophages, in the Journal: Scientific Reports Scientific Reports
• what: The authors demonstrate that AcrAB contributes to the survival of AIEC LF82 in the macrophage environment as evidenced by increased bacterial death after infection of THP1-derived macrophages with a AcrAB-defective mutant (LF82 u0394acrAB).
• how: To investigate on the phenotype induced by AcrB inhibition the authors carried out infection experiments of THP-1 cells differentiated into macrophages . . .
  

   

  

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