HIGHLIGHTS
- who: Xiaonan Xi from the (UNIVERSITY) have published the research work: ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in glioma, in the Journal: (JOURNAL)
- what: The authors investigated the effects of on glioma cell proliferation and clarified its mechanism. The authors report that PAI-1 is overexpressed in glioma tissues and cell lines. The authors demonstrate that ACT001 can enhance the antitumour effects of cisplatin in_vitro and in_vivo. added for the wounding healing assay, cell invasion assay, apoptosis assay and tube formation assay. The . . .
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