Activated astrocytes attenuate neocortical seizures in rodent models through driving na+-k+-atpase

HIGHLIGHTS

• who: Junli Zhao from the Animals Adult (males, months) GFAP-Cre mice, CaMKIIu03b1-Cre mice and Sprague Dawley (SD) rats were used in this studyGFAP-Cre transgenic mice, which contain the, .2-kB fragment of the human GFAP promoter driving expression of Cre recombinase, surrounded by four copies of genomic insulator, were generated by Dr. K.D. McCarthy at the University of North Carolina at Chapel Hill. Adult GFAP-Cre mice express Cre recombinase protein in astrocytes but not in neurons or oligodendrocytes11, . CaMKIIu03b1-Cre transgenic mice, which have the mouse calcium/calmodulin-dependent protein kinase II . . .
  

   

  

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