Activated cdc42-associated kinase 1 (ack1) binds the sterile α motif (sam) domain of the adaptor slp-76 and phosphorylates proximal tyrosines

HIGHLIGHTS

  • who: Youg R. Thaker from the (UNIVERSITY) have published the article: Activated Cdc42-associated kinase 1 (ACK1) binds the sterile α motif (SAM) domain of the adaptor SLP-76 and phosphorylates proximal tyrosines, in the Journal: (JOURNAL) of April/14,/2017
  • what: The authors have examined the capacity of the SLP-76 SAM domain to interact with other SAM domain-carrying proteins.
  • how: These results indicated that endogenous SLP-76 could be co-precipitated with transfected ACK1 and the association was increased with anti-CD3 stimulation. The binding data showed that ACK1 sustained binding . . .

     

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