Activated endolysosomal cation channel trpml1 facilitates maturation of α-synuclein-containing autophagosomes

HIGHLIGHTS

• who: Björn H. Falkenburger from the Department of Neurology, RWTH University Aachen, Aachen, Germany, Department of Neurology, University Hospital Carl have published the research work: Activated Endolysosomal Cation Channel TRPML1 Facilitates Maturation of α-Synuclein-Containing Autophagosomes, in the Journal: (JOURNAL)
• what: Microscopy of Fixed Cells For the quantification of EGFP distribution pattern in HEK293T_cells, the analysis was carried out as previously described (Dinter et_al, 2016).
• how: For the discrimination of cytosolic aggregates from vesicles by chemically-induced dimerization the authors used A53T-α-synuclein fused to FRB (FKBP-rapamycin binding domain) and mCherry . . .
  

   

  

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