Activated protein c ameliorates tubular mitochondrial reactive oxygen species and inflammation in diabetic kidney disease

HIGHLIGHTS

  • who: Rajiv Rana and collaborators from the Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostic, University Hospital Leipzig have published the research work: Activated Protein C Ameliorates Tubular Mitochondrial Reactive Oxygen Species and Inflammation in Diabetic Kidney Disease, in the Journal: Nutrients 2022, 3138 of /2022/
  • what: The authors aimed to define whether aPC protects not only the glomerular but also the tubular compartment from excessive mitochondrial ROS generation. The authors demonstrate that aPC likewise protects against glucose- 13 of 17 work, the authors focused mostly on the glomerular compartment, and the authors were . . .

     

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