Activated signaling pathways and targeted therapies in desmoid-type fibromatosis: a literature review

HIGHLIGHTS

  • who: Erik A. C. Wiemer from the Department of Surgical Oncology, Erasmus MC-University Medical Center, Rotterdam, Netherlands, Department of Cancer Center, United States have published the research work: Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review, in the Journal: (JOURNAL)

SUMMARY

    Desmoid-type fibromatosis (DTF) is a clonal fibroblastic proliferation of the soft tissues that arises in musculoaponeurotic structures. It has a mesenchymal origin since DTF tumors express cell surface markers and genes that are characteristic of mesenchymal stem_cells. This review comprehensively screened the available literature regarding . . .

     

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