Activated t cells sustain myeloid-derived suppressor cell-

HIGHLIGHTS

• who: Top from the Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy have published the research: Activated T cells sustain myeloid-derived suppressor cell-, in the Journal: (JOURNAL)
• what: The authors show that the expression of ligands B7-H1 and MHC class II both on in vitro-induced MDSCs and on MDSCs in the tumor microenvironment of cancer patients is paralleled by an increased expression of their respective receptors PD-1 and LAG-3 on T cells two inhibitory molecules associated with T cell dysfunction. The authors further . . .
  

   

  

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