Activated trpa1 plays a therapeutic role in tmz resistance in glioblastoma by altering mitochondrial dynamics

HIGHLIGHTS

  • who: Hao Chen from the Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining, China have published the research: Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics, in the Journal: (JOURNAL)
  • what: This study shows the role played by TRPA1 in TMZ resistance in GBM and elucidates the mechanism of resistance. The aims of the study were to 1) ascertain the effect of TRPA1 regulation on the apoptosis, oxidative stress and mitochondrial function of TMZ-treated GBM cells and 2) explore the mechanism of TRPA1 to propose . . .

     

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