Activating silent glycolysis bypasses in escherichia coli

HIGHLIGHTS

• who: AAAS and collaborators from the Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg, Potsdam-Golm, Germany have published the paper: Activating Silent Glycolysis Bypasses in Escherichia coli, in the Journal: (JOURNAL) of 12/05/2022
• what: The authors aimed to fully replace the endogenous EMP glycolysis by relying on native enzymes only. The authors show that a methylglyoxal-dependent route can carry all glycolytic flux to support a high growth rate. The authors demonstrate that the operation of this synthetic route relies on a delicate balance between the rate of serine production . . .
  

   

  

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