Activation and inhibition of photoreceptor guanylyl cyclase by guanylyl cyclase activating protein 1 (gcap-1)

HIGHLIGHTS

  • who: Igor V. Peshenko from the (UNIVERSITY) have published the article: Activation and Inhibition of Photoreceptor Guanylyl Cyclase by Guanylyl Cyclase Activating Protein 1 (GCAP-1), in the Journal: (JOURNAL) of July/27,/2007
  • how: The former role is supported by the results presented in this study and the latter was also proposed previously by another group .

SUMMARY

    Binding of Mg2ⴙ in EF-hands 2 and 3 was essential for RetGC activation in the conditions mimicking light adaptation. Mg2ⴙ binding in EF-hand 4 affected neither GCAP-1 affinity for RetGC . . .

     

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