Activation of ccl21-gpr174/ ccr7 on cardiac fi broblasts underlies myocardial ischemia/ reperfusion injury

HIGHLIGHTS

  • who: . and colleagues from the University of Science and Technology of China, China have published the Article: Activation of CCL21-GPR174/ CCR7 on cardiac fi broblasts underlies myocardial ischemia/ reperfusion injury, in the Journal: (JOURNAL)
  • how: The results showed that the protein expression of CCL21 and CXCL13 was significantly increased following myocardial I/R injury . The double-labeling immunofluorescence results showed that there was no GPR174 positive cells (green) co-localized with the u03b1-Actinin positive cells (red) in the sham or myocardial I/R mice suggesting that GPR174 did not present on cardiomyocytes .
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