Activation of e2f-dependent transcription by the mouse cytomegalovirus m117 protein affects the viral host range

HIGHLIGHTS

• who: El#_#x00E9 and colleagues from the Universitätsmedizin Berlin, Berlin, GermanyEditor: Robert FKalejta, University of WisconsinMadison, UNITED STATES have published the research work: Activation of E2F-dependent transcription by the mouse cytomegalovirus M117 protein affects the viral host range, in the Journal: (JOURNAL) of November/21,/2018
• what: The authors show that the M117 protein is expressed with early kinetics localizes to viral replication compartments and contributes to the inhibition of cellular DNA synthesis. The authors show that the MCMV M117 protein interacts with all canonical E2F family members and activates E2F-dependent . . .
  

   

  

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