Activation of gαq sequesters specific transcripts into ago2 particles

HIGHLIGHTS

• who: Lela Jackson from the Department have published the paper: Activation of Gu03b1q sequesters specific transcripts into Ago2 particles, in the Journal: Scientific Reports Scientific Reports
• what: In Fig 3A, the authors compare cytosolic levels of ATP5f1b, Chgb and tau under control, Gu03b1q stimulation, heat shock, osmotic stress and Gu03b1i stimulation. The studies show that in differentiated PC12 cells, Gu03b1q activation sequesters two mRNAs important for endocrine function and cellular energy in Ago2 stress granules. The authors show similar stress granule assembly as followed by the marker protein G3BP1 and that these particles are stable . . .
  

   

  

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