Activation of gabaa receptors in colon epithelium exacerbates acute colitis

HIGHLIGHTS

  • who: Xuelian Ma and Jingxin Li from the Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan, China have published the research work: Activation of GABAA Receptors in Colon Epithelium Exacerbates Acute Colitis, in the Journal: (JOURNAL)
  • how: In light of the ability for the GABAergic system to directly suppress immune and inflammatory responses the authors considered it important to investigate the potential role and mechanism of GABA in UC. To accomplish this goal the authors examined the effects of GABA in dextran sulfate sodium (DSS)-induced mouse model of colitis and colonic . . .

     

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