Activation of p47phox, a cytosolic subunit of the leukocyte nadph oxidase

HIGHLIGHTS

  • who: Jennifer L. Johnson from the (UNIVERSITY) have published the paper: Activation of p47PHOX, a Cytosolic Subunit of the Leukocyte NADPH Oxidase, in the Journal: (JOURNAL) of September/23,/1998
  • what: The authors report here that p47PHOX-deficient B lymphoblasts expressing the p47PHOX S359A/S370A or p47PHOX S359K/S370K double mutation show dramatically reduced levels of enzyme activity and phosphorylation of p47PHOX as compared with the same cells expressing wild_type p47PHOX. The authors investigate the effect of double mutations involving serines 359 and 370 on the phosphorylation of p47PHOX and the activity of the leukocyte . . .

     

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