Activation of peripheral trpm8 mitigates ischemic stroke by topically applied menthol

HIGHLIGHTS

  • who: Shiang-Suo Huang from the Graduate Institute of Acupuncture Science, China Medical University have published the article: Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol, in the Journal: (JOURNAL)
  • what: The authors identified whether activating periphu2011 eral TRPM8 can be an adjuvant therapy for ischemic stroke. This study aimed to explore whether activation of peripheral TRPM8 by administering menthol treatment may effectively limit neurological deficits following cerebral ischemia in a mouse middle cerebral artery occlusion (MCAO) model of stroke. In this study, GFAP as the astrocytosis marker, and the microgliosis were . . .

     

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