Activation of recombinational repair in ewing sarcoma cells carrying ews-fli1 fusion gene by chromosome translocation

HIGHLIGHTS

  • who: Kazuhiro Tanaka from the DepartmentOita University have published the paper: Activation of recombinational repair in Ewing sarcoma cells carrying EWS-FLI1 fusion gene by chromosome translocation, in the Journal: Scientific Reports Scientific Reports
  • how: Using microarrays expression levels of mRNAs were assessed in K562 cells and the results were compared with those in a primary culture of normal human fibroblasts MRC-5 a scatter plot of which is shown in Fig 1A.

SUMMARY

    Expression of the RAD51 and other HR genes was remarkably upregulated, whereas NHEJ gene_expression was not significantly . . .

     

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