Activation of the janus kinase/signal transducer and activator of transcription pathway by osmotic shock*

HIGHLIGHTS

• who: Petros Gatsios from the (UNIVERSITY) have published the Article: Activation of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway by Osmotic Shock*, in the Journal: (JOURNAL) of November/17,/1997
• what: The authors demonstrate that in different cell lines a particular stress, namely hyperosmolarity, results in tyrosine phosphorylation of the Janus kinases Jak1, Jak2, and Tyk2 and in the activation of STAT1 and/or STAT3. The authors demonstrate that hyperosmotic shock activates the Jak/STAT pathway.

SUMMARY

Environmental stress (UV light, heat, aniso-osmolarity, and radicals) has recently . . .

 



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