Activation of the notch signaling pathway in vivo elicits changes in csl nuclear dynamics

HIGHLIGHTS

• who: Maria J. Gomez-Lamarca from the Department University of Cambridge, Downing Street, Cambridge , DY, UK have published the paper: Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics, in the Journal: CSL. CSL is highly dynamic with transient of March/12,/2018
• what: In vivo activity triggers changes in CSL dwell times and chromatin accessibility which the authors propose confer sensitivity to small input changes and facilitate timely shut-down. The authors propose that the localized chromatin remodeling brought about by Su(H)NICD reduces obstacles (e_g, moves nucleosomes . . .
  

   

  

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