Activation of zebrafish src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of e-cadherin/β-catenin complexes in vivo

HIGHLIGHTS

• who: Emily Sempou from the Department of Biology, University of Konstanz, Constance, Germany have published the paper: Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo, in the Journal: (JOURNAL)
• what: The authors report that the Src family kinases (SFKs) Fyn and Yes act downstream of PrP-1 to prevent the endocytosis and degradation of adhesion complexes in vivo. The experiments show that PrP-1 positively modulates the levels and activity of SFKs in the gastrula . . .
  

   

  

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