Active intermixing of indirect and direct neurons builds the striatal mosaic

HIGHLIGHTS

  • who: Andrea Tinterri from the Ecole Normale Paris, Paris, France, Boehringer Ingelheim Fonds, Foundation for Basic Research in Medicine, Schusterstr., Mainz, Germany. UPMC University have published the research: Active intermixing of indirect and direct neurons builds the striatal mosaic, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Taken together, the work shows that dSPN and iSPN form segregated embryonic populations that intermix over time, first in the lateral early-born proto-striosomes and then in the medial region. The authors show that while dSPN and iSPN differentiation is largely independent, their intermixing relies on a . . .

     

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