Active targeting of p-selectin by fucoidan modulates the molecular profiling of metastasis in docetaxel-resistant prostate cancer

HIGHLIGHTS

  • who: Chang-Hsun Ho and collaborators from the Department of Anesthesiology, Show Chwan Memorial Hospital, Changhua, Taiwan Department of Pharmacy, National Yang Ming Chiao Tung University, Taipei, Taiwan have published the Article: Active Targeting of P-Selectin by Fucoidan Modulates the Molecular Profiling of Metastasis in Docetaxel-Resistant Prostate Cancer, in the Journal: (JOURNAL)
  • what: The study shows that the biological activity of fucoidan has an important application for docetaxel-resistant PCa cells inhibiting IL-1R by binding to P-selectin and reducing the expression levels of NF-u03baB p50 and Cox2 in this metastasis . . .

     

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