Activin a reduces girk current to excite dentate gyrus granule cells

HIGHLIGHTS

  • who: Christian Alzheimer and Fang Zheng from the Hokkaido University, Japan have published the article: Activin A Reduces GIRK Current to Excite Dentate Gyrus Granule Cells, in the Journal: (JOURNAL)
  • what: The study shows that EE enhances the excitability of GCs in an activin-dependent fashion.

SUMMARY

    Activin A was originally identified as a neurotrophic and neuroprotective factor, but more recent evidence from the and other laboratories implicated activin signaling also in the modulation of the neurophysiological underpinnings of cognitive functions, affective behavior, and drug addiction (Ageta and Tsuchida, 2011; Krieglstein . . .

     

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