Acute antagonism in three-drug combinations for vaginal hiv prevention in humanized mice

HIGHLIGHTS

  • who: Philippe A. Gallay from the DepartmentUniversity of have published the Article: Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice, in the Journal: Scientific Reports Scientific Reports
  • future: Future studies should determine the effect of omitting FTC rather than TDF from these combinations.

SUMMARY

    The extensive systemic and genital mucosal reconstitution with human lymphoid cells renders female BLT hu-mice susceptible to vaginal HIV-1 infection. The overall vaginal HIV-1 prevention study design using female BLT hu-mice has been described ­previously25-27, and is . . .

     

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