Acute effect of antiseizure drugs on background oscillations in scn1a dravet syndrome mouse model

HIGHLIGHTS

  • who: March and colleagues from the South Central of for Nationalities, China have published the Article: Acute effect of antiseizure drugs on background oscillations in Scn1a Dravet syndrome mouse model, in the Journal: (JOURNAL)
  • what: Utilizing DS mice (Scn1aA1783V/WT) the authors show that acute administration of Dravetrecommended drugs, VA, CLB, a combination of CLB + STP, or STP alone, was associated with a reduction in the frequency of interictal spikes in most of the tested mice, along with a significant increase in relative beta band contribution to the total power. The authors focused on the . . .

     

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