Adam17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice

HIGHLIGHTS

  • who: P M Vidal from the DepartmentHasselt University, Kiel, Germany have published the Article: ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice, in the Journal: (JOURNAL)
  • what: The analysis showed a slight but non-significant increase in the number of apoptotic oligodendrocytes caudal to the lesion site (data not shown). The authors show for the first time that ADAM17 inhibition leads to a concentration-dependent modulation of p44 MAPK phosphorylation in microglia and oligodendrocyte cultures.
  • how: The authors used the following cell . . .

     

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