Adamts4-specific mr probe to assess aortic aneurysms in vivo using synthetic peptide libraries

HIGHLIGHTS

• who: Jan O. Kaufmann from the Universitu00e4t of Chemistry, Brook-Taylor-Str2, Berlin, Germany. Universidad Catu00f3lica de have published the Article: ADAMTS4-specific MR probe to assess aortic aneurysms in vivo using synthetic peptide libraries, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show, that by screening a fully synthetic OBOC library the authors were able to identify a selective binder against ADAMTS4. The authors focused on a cycle containing four fully randomized amino_acids out of the eleven canonical amino_acids, framed by two cysteines to form a cycle by a disulfide_bridge (Fig 1a . . .
  

   

  

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