Adaptation of pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor c- 30 during experimental evolution requires multiple genotypic and phenotypic changes

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  • who: Bovu00e9 et_al et al. from the (UNIVERSITY) have published the Article: Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C- 30 during experimental evolution requires multiple genotypic and phenotypic changes, in the Journal: (JOURNAL)
  • what: The authors evaluated the fitness antimicrobial susceptibility metabolic activity gene expression in vitro production of virulence factors and in vivo virulence of experimentally evolved Pseudomonas aeruginosa PAO1. This study shows that mutations acquired during experimental evolution of P. aeruginosa biofilms in the presence of tobramycin and C-u00ad30 are accompanied by an altered fitness metabolism . . .

     

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