Adaptation proteins in the medial prefrontal cortex

HIGHLIGHTS

  • who: ISRN Psychiatry et al. from the University of, POBox, , have published the research: Adaptation Proteins in the Medial Prefrontal Cortex, in the Journal: (JOURNAL) of 12/Nov/2012
  • what: The authors applied a standard phencyclidine treatment protocol, produced a measureable behavioural deficit in spontaneous alternation behavior, and could provide evidence of neuroadaptation of this via proteomics analysis of the medial prefrontal cortex. Several of the hits in this study have also appeared in clinical postmortem studies of the brains of individuals with schizophrenia, thus further validating the use of phencyclidine as a model of . . .

     

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