Adar rna editing on antisense rnas results in apparent u-to-c base changes on overlapping sense transcripts

HIGHLIGHTS

SUMMARY

    Editing sites can be detected by directly comparing RNAseq to DNA-seq data or a reference genome (Levanon et_al, 2004; Picardi and Pesole, 2013; Wang et_al, 2016; John et_al, 2017; Piechotta et_al, 2017). Several bioinformatics pipelines have been developed for the analysis of next-generation sequencing (NGS) data to detect RNA editing sites (Ramaswami and Li, 2016; Eisenberg and Levanon, 2018; Diroma et_al, 2019), leading to a constant increase of entries in their catalogs and the generation of new databases (Kiran and Baranov, 2010; Ramaswami and Li, 2014; Picardi et_al, 2017; Mansi et_al, 2021 . . .

     

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