HIGHLIGHTS
- who: Kehan Zhang from the Chongqing Medical University, Chongqing, China have published the research: ADAR1p110 promotes, in the Journal: (JOURNAL)
- what: The authors report that the promotion of EV-D68 replication by ADAR1 correlates with its RNA-editing activity and inhibition of PKR activation. The study demonstrated that ADAR1p110 could inhibit the activation of PKR signaling after EV-D68 infection.
- how: RT-qPCR results showed that the mRNA level of ADAR1 decreased after viral infection (Fig 1I J) indicating that ADAR1 is probably regulated at the transcriptional level after viral infection. The results . . .
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