HIGHLIGHTS
SUMMARY
For the detection of ADCC-mediating serum antibodies induced after vaccination with existing or novel candidate universal influenza, the availability of reliable assays, suitable for standardization, is required. The authors compiled antibody-dependent cellular cytotoxicity (ADCC) data obtained in four separate studies to get a comprehensive overview of the induction of ADCC-mediating antibodies after influenza virus infection, or immunization with monovalent, trivalent, or quadrivalent influenza vaccines. Together, the authors showed that influenza virus infection and influenza vaccination led to the induction of ADCC-mediating antibodies, which can be rapidly recalled by re-infection . . .
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