Addovenom: thermostable protein-based addomer nanoparticles as new therapeutics for snakebite envenoming

HIGHLIGHTS

  • What: The authors anticipate that the approaches described here will produce antivenom with unparalleled efficacy safety and affordability. The authors seek to develop ADDomers and ADDobodies with neutralising capabilities against Echis SVMPs, PLA2 s and disintegrins and mamba 3FTx and Kunitz-type toxins, using the approaches shown in Figure 2. Once more, ensuring and GMP willproduct be combined with downstream optimisation, ensuringprocess a good scalability compromise between compatibility are theloss main focus. a continuous has beenand a purity and product along theMoving process.towards Once more, ensuringbioprocess process scalability major as the are higher automation will leadtowards . . .

     

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