Adenosine 2 receptor regulates autophagy and apoptosis to alleviate ischemia reperfusion injury in type 2 diabetes via ire-1 signaling

HIGHLIGHTS

  • who: Mohamed Bassirou Moukeila Yacouba from the Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China have published the Article: Adenosine 2 receptor regulates autophagy and apoptosis to alleviate ischemia reperfusion injury in type 2 diabetes via IRE-1 signaling, in the Journal: (JOURNAL)
  • what: The authors examined whether A2R activation regulates ERS induced autophagy in diabetic rats to offer cardio protection during MIRI, and the mechanism involved. Given the upregulation of CHOP and caspase 12 in the experiment , the authors investigated ERS involvement in the resultant autophagy and apoptosis using the ERS . . .

     

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