HIGHLIGHTS
- who: Xinli Xu from the University of have published the Article: Adenosine A2A receptors control synaptic remodeling in the adult brain, in the Journal: Scientific Reports Scientific Reports
- what: This study shows that the overactivation of A 2ARs is a molecular mechanism underlying synaptic remodeling in the injured brain, namely SE-induced hippocampal MF sprouting.
SUMMARY
Forty-two days after SE induction, a positive Timm staining demonstrated MF sprouting in the granule cell and molecular layers of the DG (Fig 3a,b). In rats administered with SCH58261, SE still induced a . . .
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