Adenosine a2a receptors shut down adenosine a1 receptor-mediated presynaptic inhibition to promote implementation of hippocampal long-term potentiation

HIGHLIGHTS

• who: Cu00e1tia R. Lopes and collaborators from the CNC-Center for Neuroscience and Cell Biology, University of, have published the research work: Adenosine A2A Receptors Shut Down Adenosine A1 Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation, in the Journal: Biomolecules 2023, 715 of /2023/
• what: This study was designed to test: (i) if extracellular adenosine does indeed build up in synapses according to the increased recruitment of hippocampal excitatory synapses, and_(ii) if A2A R do indeed play a key role in dampening A1 R during LTP induction to allow . . .
  

   

  

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