HIGHLIGHTS
- who: Jiao Peng and collaborators from the Monash University, Australia have published the paper: Adiponectin Deficiency Enhances Anti-Tumor Immunity of CD8+ T Cells in Rhabdomyosarcoma Through Inhibiting STAT3 Activation, in the Journal: (JOURNAL)
- what: The authors investigated the role APN on CD8+ T_cells in the tumor microenvironment of rhabdomyosarcoma-bearing mice, and found that APN deficiency inhibited rhabdomyosarcoma growth, which was associated with enhancing the anti-tumor response of CD8+ T_cells that infiltrated rhabdomyosarcoma through the inhibition of STAT3 activation. with or without radiotherapy . This study demonstrated that APN deficiency could promote CD8+ T_cell . . .
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