Adoptive nk cell transfer as a treatment in colorectal cancer patients: analyses of tumour cell determinants correlating with efficacy in vitro and in vivo

HIGHLIGHTS

• who: Pilar M. Lanuza from the The University of Queensland, Australia have published the Article: Adoptive NK Cell Transfer as a Treatment in Colorectal Cancer Patients: Analyses of Tumour Cell Determinants Correlating With Efficacy In Vitro and In Vivo, in the Journal: (JOURNAL)
• what: Using transcriptomics and immunohistochemistry (IHC) data in a large cohort of CRC patients, the authors demonstrate a positive correlation between HLA-A downmodulation and survival in early-stage MSI tumours, which is associated with NK cell infiltration. The authors demonstrate that HLA-A downmodulation correlates a with better prognosis in MSI . . .
  

   

  

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