Adp-ribose transferase parp16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion

HIGHLIGHTS

  • who: Posted Date September et al. from the Ethical statement All animals and the experimental protocol conformed to the Animal Welfare Act Guide for Use and Care of Laboratory Animals, and were approved by Institutional Animal Care and Use Committee (IACUC), Fudan University, China have published the article: ADP-ribose Transferase PARP16 Mediated-unfolded Protein Response Contributes to Neuronal Cell Damage in Cerebral Ischemia/Reperfusion, in the Journal: (JOURNAL)
  • what: The authors report ER-associated tail-anchored protein PARP16 selectively (ADP-ribosyl)ates PERK and IRE1u03b1 during the UPR, and that such modification lead to . . .

     

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