Adult re-expression of irsp53 rescues nmda receptor function and social behavior in irsp53-mutant mice

HIGHLIGHTS

  • who: Young Woo Noh from the Korea Advanced Institute Korea University have published the article: Adult re-expression of IRSp53 rescues NMDA receptor function and social behavior in IRSp53-mutant mice, in the Journal: (JOURNAL) of 11/Nov/2021
  • what: Discussion the study demonstrates that adult re-expression by BBBpenetrant PHP.eB-mediated gene delivery can lead to the restoration of NMDAR function and social behavior in IRSp53cKO These results suggest that adult re-expression has clinical potential for IRSp53-related brain disorders.
  • how: The authors set out to direct adult reexpression using . . .

     

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