Advanced image analysis methods for automated segmentation of subnuclear chromatin domains

HIGHLIGHTS

  • who: Philippe Johann to Berens and collaborators from the Institut de Biologie Molu00e9culaire des Plantes du CNRS, Strasbourg, France have published the paper: Advanced Image Analysis Methods for Automated Segmentation of Subnuclear Chromatin Domains, in the Journal: Epigenomes 2022, 34 of /2022/
  • what: The authors report the development of two complementary segmentation methods one semi-automated (iCRAQ) and one based on deep learning (Nucl.Eye.D) and their evaluation using a collection of A. thaliana nuclei with contrasted or poorly defined chromatin compartmentalization. This analysis shows that, for nuclei segmentation, DL-based methods exhibit a . . .

     

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