Advancing age decreases pressure-sensitive modulation of calcium signaling in the endothelium of intact and pressurized arteries

HIGHLIGHTS

  • who: meiersa from the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, and Durham, UK have published the article: Advancing Age Decreases Pressure-Sensitive Modulation of Calcium Signaling in the Endothelium of Intact and Pressurized Arteries, in the Journal: (JOURNAL)
  • what: In the present study, responses in aged (18-monthold) and young (3-month-old) rats were compared. The authors investigated endothelial i signaling responses to ACh using gradient index (GRIN) fluorescence endomicroscopy . The main focus of the latter study was atherosclerosis development, and hence younger animals were used. The GRIN imaging . . .

     

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