HIGHLIGHTS
- who: . et al. from the The University of Sheffield, United Kingdom have published the paper: Advantages of CRISPR-Cas9 combined organoid model in the study of congenital nervous system malformations, in the Journal: (JOURNAL)
- how: The results showed that compared with the control group the brain organoids of patients showed smaller neuroepithelial areas and changed the spindle direction of radial glial cells.
SUMMARY
The brain organoid is a 3D tissue model of autologous development derived from omnipotent or pluripotent stem_cells, which can summarize the whole process of neurodevelopment, including neurogenesis, gliogenesis . . .
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