Aedes aegypti clipb9 activates prophenoloxidase-3 in the presence of clipa14 after fungal infection

HIGHLIGHTS

  • who: Yannan Ji from the Southwest University, China have published the research work: Aedes aegypti CLIPB9 activates prophenoloxidase-3 in the presence of CLIPA14 after fungal infection, in the Journal: (JOURNAL)
  • what: The authors focused on CLIPA14 first. The experiments demonstrated that CLIPA14 acts as a cofactor of CLIPB9 in the antifungal immune melanization. The authors successfully obtained the soluble proCLIPB9 . The authors propose a new model of the Ae. aegypti immune melanization pathway in response to fungal infection .
  • how: Structural features purification and activation of recombinant proCLIPB9 Data were analyzed using GraphPad . . .

     

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