Aerobic exercise alleviates abnormal autophagy in brain cells of app/ps1 mice by upregulating adipor1 levels

HIGHLIGHTS

  • who: Ye Jian et al. from the Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, China have published the research work: Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels, in the Journal: (JOURNAL)
  • what: The results of the study showed that APP/PS1 double transgenic AD model mice (24 weeks) showed decreased levels in the brain abnormal autophagy increased Au03b2 deposition and increased cell apoptosis and dendritic spines and cognitive function were reduced. The authors measured the antiapoptotic protein B-cell . . .

     

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