Aerobic exercise facilitates the nuclear translocation of srebp2 by activating akt/sec24d to contribute cholesterol homeostasis for improving cognition in app/ps1 mice

HIGHLIGHTS

• who: Zelin Hu et al. from the Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, China have published the research work: Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice, in the Journal: (JOURNAL) of 14/08/2023
• what: Within this study, the authors examined the impacts of aerobic exercise on brain cholesterol synthesis in APP/PS1 transgenic mice.
• how: This result indicated that aerobic exercise effectively improved AKT inhibition in the brains . . .
  

   

  

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