Af8c multi-kinase inhibitor induces apoptosis by activating dr5/nrf2 via ros in colorectal cancer cells

HIGHLIGHTS

  • who: Soyeon Jeong and collaborators from the Division of Oncology/Hematology, Department of Internal Medicine, College of Medicine, University have published the Article: AF8c Multi-Kinase Inhibitor Induces Apoptosis by Activating DR5/Nrf2 via ROS in Colorectal Cancer Cells, in the Journal: (JOURNAL)
  • what: The authors decided to explore the ability of AF8c, as a kinase inhibitor, to inhibit the phosphorylation of the ERBb family members in the 7 of 17 cellular context.
  • how: Data were analyzed using unpaired Student's t-tests. The results showed that AF8c inhibits the phosphorylation of all . . .

     

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