Affinity maturation of the rlip76 ral binding domain to inform the design of stapled peptides targeting the ral gtpases

HIGHLIGHTS

• who: Catherine A. Hurd from the Catherine AHurd1, Paul Brear1, Jefferson Revell2, Sarah Ross3, Helen R. Mott1, *, and Darerca Owen1, * From the Department of Biochemistry, University of Cambridge, Cambridge, UK have published the research: Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases, in the Journal: (JOURNAL) of August/27,/2020
• what: The authors aimed to use the insights gained from the CIS display selections to improve the affinity of the first-generation stapled peptides targeting the Ral GTPases. The compounds they developed are currently . . .
  

   

  

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