African swine fever virus transmembrane protein pep84r guides core assembly

HIGHLIGHTS

• who: Alu00ed Alejo and colleagues from the Biologu0131u0301a Molecular Severo OchoaBiologu0131u0301a Molecular Severo Ochoa have published the article: African swine fever virus transmembrane protein pEP84R guides core assembly, in the Journal: (JOURNAL) of January/30,/2023
• what: The authors report the functional characterization of pEP84R a polypeptide embedded in the inner envelope that surrounds the viral core. Using an ASFV recombinant inducibly expressing the EP84R gene the authors show that absence of pEP84R results in the formation of non-infectious core-less icosahedral particles displaying a significant DNA-packaging defect. This study characterizes the viral . . .
  

   

  

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